BHRT (Bioidentical Hormone Replacement Therapy) versus HRT (Hormone Replacement Therapy)

Both therapies include the use of hormones to address hormonal imbalances or deficiencies, but they differ in the type of hormones used and how they are formulated.

• HRT (Traditional Hormone Replacement Therapy):

  • Typically uses synthetic hormones that are chemically similar but not identical to the hormones made in the human body.

  • Common synthetic hormones used include conjugated estrogens (e.g., Premarin), synthetic progestins (e.g., Provera), and estradiol (in some forms).

  • Progestins differ from natural progesterone and can have different effects in the body.

• BHRT (Bioidentical Hormone Replacement Therapy):

  • Uses hormones that are chemically identical to the ones naturally produced by the human body.

  • These hormones are characteristically derived from plant sources, such as yams or soy, and are synthesized to match the molecular structure of human hormones.

  • Common hormones used in BHRT include bioidentical estradiol, bioidentical progesterone, bioidentical testosterone, and bioidentical DHEA.

• HRT (Traditional Hormone Replacement Therapy):

  • Typically prescribed in standard doses and forms (e.g., pills, patches, gels, or injections).

  • Some forms of HRT (like oral pills) can have greater risks of side effects due to liver processing, while others (like transdermal patches) may have a lower risk of certain side effects like blood clots.

• BHRT (Bioidentical Hormone Replacement Therapy):

  • Regularly customized to the individual's specific needs and hormone levels, sometimes using compounded formulations (hormones mixed by a pharmacist in the exact dosage and form prescribed).

  • BHRT can be delivered in various forms, including pills, patches, creams, gels, and even pellets inserted under the skin.

  • The capability to tailor treatment is a key selling point of BHRT, though it's important to note that compounded forms are not FDA-approved and can carry risks.

• HRT (Traditional Hormone Replacement Therapy):

  • Traditional HRT has been in use for decades and is supported by extensive research and clinical trials.

  • While HRT is successful for managing symptoms of menopause and hormonal imbalances, its synthetic hormones may cause side effects in some women, such as increased risk of blood clots, breast cancer, or cardiovascular issues, particularly with long-term use.

  • There are guidelines and well-established protocols for prescribing traditional HRT, which is often seen as more regulated.

• BHRT (Bioidentical Hormone Replacement Therapy):

  • BHRT is often promoted as a "natural" alternative to synthetic HRT, with a focus on using hormones that match the body's own biochemistry.

  • It is disputed that because the hormones are identical to those produced by the body, they are better tolerated and result in fewer side effects.

  • The scientific evidence comparing the safety and effectiveness of BHRT to traditional HRT is constantly evolving. Some studies suggest that BHRT may offer similar risks and benefits to traditional HRT. But, when you deep dive further into research it is shown that BHRT is safe and efficacious and the preferred hormone replacement therapy. 

  • One of the criticisms of BHRT is the lack of regulation and standardization, especially with compounded hormones, which are not FDA-approved.

• HRT (Traditional Hormone Replacement Therapy):

  • Risks include increased likelihood of blood clots, stroke, heart disease, and breast cancer, particularly with combined estrogen and progestin therapy.

  • The risks fluctuate depending on the formulation, delivery method, and individual health factors.

• BHRT (Bioidentical Hormone Replacement Therapy):

  • Since BHRT uses hormones identical to those in the body, it is often marketed as safer, with fewer side effects. However, side effects can still occur, such as headaches, mood changes, bloating, or increased risk of blood clots (depending on the type of hormones and delivery methods).

  • Because BHRT is not as extensively researched and lacks standardization, there is less clarity about long-term risks.

• Both HRT and BHRT are effective at treating symptoms of menopause, such as hot flashes, night sweats, vaginal dryness, and mood swings. 

• BHRT can be life-long treatment and preventative against many age related conditions such as cardiovascular disease, certain cancers, diabetes, Alzheimer’s, obesity, osteoporosis

Both BHRTand HRT are viable options for hormone replacement therapy, but they differ in the type of hormones used, their formulation, and customization. HRT is based on synthetic hormones with decades of research supporting its use, while BHRT uses hormones that are biologically identical to human hormones and is often marketed as a more natural, customizable treatment option. BHRT can be tailored specifically to your symptoms, age, and goals.

Ready to explore which hormone therapy is right for you? At Inner Bliss Care, our team is here to provide personalized guidance and support for your unique needs. Reach out to us today to schedule a consultation and start your journey to balanced health and well-being.